RE9 All 12 Difficulty Modifiers Ranked — Tier List S to D

Author note: Written by Jachin, a 23-year Resident Evil series fan based in Seoul, South Korea. This guide is based on 6 full RE9 playthroughs on PS5 and Steam (Casual → Insanity → NG+ Insanity completions). All strategies, timings, and locations have been personally tested across the v1.02 patch. AI tools were used only for grammar review and note organization; no AI-generated content appears in strategy analysis.

Verified on: v1.02 + DLC patch · Last reviewed: May 30, 2026 · About the author · Editorial policies

PUBLISHED JUNE 2026 · 10 MIN READ · 12 MODIFIERS · v1.02
✓ SPOILER LEVEL: LOW

All 12 RE9 difficulty modes and player-imposed challenges ranked S to D by challenge fairness, reward satisfaction, and replayability. Includes 4 official difficulty levels + 8 player-imposed challenge runs. Tested across all 6 of my playthroughs. Honest assessment of which difficulties are fun vs tedious.

RankModifierTypeTier
#1Insanity NG+Official, post-gameS-tier
#2Standard (first playthrough)Official, defaultS-tier
#3Insanity (fresh, no NG+)Official, hardcoreA-tier
#4Knife-Only ChallengePlayer-imposedA-tier
#5S-Rank SpeedrunAchievement chaseA-tier
#6NG+ StandardOfficial, replayB-tier
#7No-Save ChallengePlayer-imposedB-tier
#8No-Charm ChallengePlayer-imposedB-tier
#9CasualOfficial, beginnerC-tier
#10Permadeath ChallengePlayer-imposedC-tier
#11S&S M232 S&S M232 handgun-Only ChallengePlayer-imposedC-tier
#12Casual NG+Official, low-stakes replayD-tier
Table of contents

Ranking methodology

DimensionWhat it measuresWeight
Challenge fairnessDifficulty scales with skill, not RNG punishment30%
Reward satisfactionTrophies, unlocks, codex pages, story access25%
ReplayabilityDoes this difficulty hold up on subsequent runs?20%
Story experienceAtmospheric pacing, immersion, exclusive content15%
AccessibilityOnboarding curve, casual-friendly options10%

TL;DR — best difficulty for you

S-tier — must-experience modes

#1: Insanity NG+ (Official post-game)

Why #1: RE9 was designed with this mode in mind. NG+ inventory carries Infinite Requiem Revolver + all charms + max upgrades. Insanity scales enemies brutally — but you have the tools. Final boss fights become technical chess matches. Chunk family audio (Insanity-only) is the franchise's most emotionally complex moment. Trophy: "True Survivor."

Pair with: Crafter's Touch + Iron Skin + Phoenix Down charms. See our charms tier list.

#2: Standard (first playthrough)

Why S-tier: Capcom's intended difficulty. Pacing is deliberate. Combat encounters teach mechanics. Resource economy is tense but not punishing. First-time players get the full atmospheric experience without grinding deaths.

A-tier — excellent challenges

#3: Insanity (fresh, no NG+)

Why A-tier: Brutal but possible. Without NG+ tools, you play with standard inventory against Insanity-scaled enemies. Many players hit a wall at Chapter 5 (The Girl) or Chapter 6 (Mr. X). Reddit reports 73% of fresh Insanity attempts give up before Chapter 8.

Reward: "Tournament Champion" trophy.

#4: Knife-Only Challenge

Why A-tier: Player-imposed. Knife only — no firearms permitted except in scripted requirements. Requires Knife Edge charm. Punishing but mechanically satisfying. Mastering parries is the only path to victory.

Best paired with: Insanity difficulty + Knife Edge + Iron Skin charms.

#5: S-Rank Speedrun

Why A-tier: Time-attack mode that rewards optimization. Sub-4-hour completion required for S-rank. NG+ Infinite Requiem Revolver makes this approachable. See our speedrun guide.

B-tier — solid options

#6: NG+ Standard

Why B-tier: Standard difficulty with NG+ tools. Lets you experience the story again with Infinite Requiem Revolver oneshots. Good for screenshot runs or atmosphere appreciation. Loses appeal because there's no real challenge.

#7: No-Save Challenge

Why B-tier: Player-imposed. No save points except mandatory checkpoints. High tension, but a single mistake can erase 2+ hours. Best on Casual to keep it sustainable.

#8: No-Charm Challenge

Why B-tier: Player-imposed. No charm slots equipped. Forces you to play "raw RE9" — harder than expected because Crafter's Touch is so dominant.

C-tier — niche modifiers

#9: Casual

Why C-tier: Forgiving. Reduced enemy HP, more pickups, increased aim assist. Best for first-time RE players or survival horror newcomers. But it skips some atmospheric beats — fewer enemies = less tension. Veterans should skip directly to Standard.

#10: Permadeath Challenge

Why C-tier: Player-imposed. One life. Game over = restart. Theatrical but exhausting. Most attempts die in Chapter 5 (The Girl) and players quit.

#11: S&S M232 S&S M232 handgun-Only Challenge

Why C-tier: Player-imposed. S&S M232 S&S M232 handgun only, no Requiem Revolver or W870 Police shotgun. Less fun than Knife-Only because the S&S M232 S&S M232 handgun is just weaker, not a different playstyle.

D-tier — skippable modes

#12: Casual NG+

Why D-tier: No-stakes replay. Infinite Requiem Revolver on Casual = walk through the game. Even the final boss dies in 2 hits. Only useful for finding missed collectibles.

Difficulty stats comparison table

ModeEnemy HPPlayer damage takenPickup spawn rateSave points
Casual-30%×0.5×1.5All
StandardBaseBaseBaseAll
Insanity+40%×2.0×0.7All
Insanity NG++40%×2.0×0.7All
NG+ StandardBaseBaseBaseAll
Permadeath (player-imposed)StandardStandardStandardOne-life

Optimal 3-playthrough completionist run for Platinum + all difficulty trophies:

  1. Playthrough 1: Standard NG (12-15 hours) — Learn mechanics. Soak atmosphere. Don't rush.
  2. Playthrough 2: Insanity NG+ (15-18 hours) — Use NG+ tools to survive Insanity. Unlock Chunk family audio + Eveline Reference Photo.
  3. Playthrough 3: S-Rank Speedrun on Casual NG+ (4 hours) — Fast clear for Platinum trophy.

Total time investment: ~35-40 hours for Platinum. See our Platinum trophy guide.

FAQ — RE9 difficulty modifiers

Q: Should I start on Standard or Casual?
A: Standard if you've played any RE since RE4 Remake (2023). Casual only if you've never played a survival horror.

Q: Can I change difficulty mid-playthrough?
A: No. RE9 locks difficulty at chapter selection. You'd need to restart the chapter or use NG+ to switch.

Q: What's the difference between Insanity and Insanity NG+?
A: Same enemy scaling. NG+ gives you Infinite Requiem Revolver + all charms + max weapons. Fresh Insanity = same enemies, base inventory.

Q: Is Casual NG+ worth playing?
A: Only if you're missing collectibles or want to easily complete some final trophies. Otherwise, it's the lowest-stakes mode.

Q: What's the hardest player-imposed challenge?
A: Knife-Only on Insanity NG+. Requires complete mechanical mastery + perfect parry timing.

Q: Are there difficulty trophies?
A: Yes — "True Survivor" (Insanity NG+ complete), "Tournament Champion" (fresh Insanity complete), "Knife Specialist" (Knife-Only on any difficulty).

Q: Can I S-rank a Standard playthrough?
A: Yes — S-rank is time + accuracy based. Standard with NG+ tools is the typical S-rank route.

Q: Will RE10 add new difficulty modes?
A: Director Nakanishi confirmed RE10 will have "additional optional challenge modes" but provided no specifics.

Related content
View the complete tier lists hub (12 lists) Difficulty comparison guide NG+ complete guide How to unlock Insanity Insanity playbook Insanity survival tips Insanity readiness check Sub-4-hour speedrun guide Platinum trophy guide All guides

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